EFFECT OF MORINGA OLEIFERA (MORINGA) AND AZADIRACHTA INDICA (NEEM) LEAF MEALS ON THE PERFORMANCE OF BROILER CHICKENS ON POULTRY DIET

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ABSTRACT

Effect of Moringa oleifera (Moringa) and Azadirachta indica (Neem) leaf meals as feed ingredients in diets for broiler chickens was evaluated. Six isonitrogenous and isocaloric diets represented as treatments 1 (control, 0% leaf meal), 2 (5% MOLM), 3 (5% AILM), 4 (2.5%AILM+ 2.5% MOLM), 5 (3% MOLM + 2% AILM), and 6 (2% MOLM + 3% AILM) were fed to one hundred and forty four Agrited broiler chicks for 49 days in a completely randomized design. The six treatments were in triplicates of eight (8) birds per replicate. Birds were offered feed and water ad-libitum. The parameters measured were live weight, weight gains, and feed consumed. Feed conversion ratio and costs in terms of feed cost per kilogram weight gain, cost per kilogram of feed, and cost of feed consumed were calculated. Carcass response, organ response and haematological parameters were also obtained after the 49 day trial. Dietary leaf meals supplemented groups revealed variable results in feed intake, weight gain, and haematological indices. The results showed that, the daily feed intake and daily weight gain of broiler chickens on T4 diets recorded the highest values (141.33g) and (49.66g) respectively which differed (P < 0.05) from values obtained for birds on T2, T3, T5 and T6. Final body weight at 8 weeks was recorded highest among birds on treatment 1 but did not significantly differ (P>0.05%) from those on treatment 4. However, for the feed conversion ratio, T4 recorded the best value (2.53) which differed (P < 0.05) from those of T1, T2, T3, T5 and T6. The cost of feed/kg did not differ significantly (P > 0.05). The cost of production/bird was significantly high (P<0.05) in T6 when compared to those of T1, T2, T3, T4 and T5. Cut-parts and organ proportions presented as a percentage dressed weight showed no significant (P > 0.05) differences. Haematology and serum biochemistry values were in conformity with standards for healthy broiler chickens. It is therefore, concluded that combining 2.5% of Moringa oleifera with 2.5% of Azadirachta indica leaf meals as feed ingredients in broiler starter and finisher diets encouraged healthy growth and may serve as supplements for antibiotics, especially when birds are reared where there is minimal access to veterinary service and in organic poultry production practices.






TABLE OF CONTENTS


Title Page                                                                                                             i

Certification                                                                                                ii

Declaration                                                                                                iii

Dedication                                                                                                  iv

Acknowledgements                                                                                     v

Table of Contents                                                                                                     vi

List of Tables                                                                                                        xi

Abstract                                                                                                                                  xii


CHAPTER 1: INTRODUCTION

1.1  Background of the Study                                                                                                           1

1.2  Statement of Problem                                                                                                      4

1.3  Objective of the Study                                                                                                           5

1.4  Justification                                                                                                6


CHAPTER 2:  LITERATURE REVIEW

2.1  Leaf Meal as Feed Material for Poultry Feed                                                                                                            8

2.2  Origin and Botanical Description of Moringa plant                                                                                                            9

2.2.1  Propagation                                                                                                                   10

2.2.2  Flowering                                                                                                  10

2.2.3  The fruit                                                                                                           10

2.2.4  The leaf                                                                                                                   11

2.3  Nutritive Value of Moringa oleifera Leaf Meal                                                                                                                   11

2.4  Inclusion level of Moringa oleifera Leaf Meal in Broiler Chicken Diet                                                                                                           13

2.5  Immunology Phytochemicals                                                                                        14

2.6  Other uses of Moringa oleifera                                                                                                      16

2.7  Anti-nutritional factors in Moringa oleifera                                                                                                     17

2.7.1  Alkaloids                                                                                                  18

2.7.2  Phytate                                                                                                      18

2.7.3  Saponin                                                                                                     19

2.7.4  Tannins                                                                                                     19

2.8  Botanical Description of Neem Plant (Azadirachta indica)                                                                                                       20

2.9  Nutritional Values of Azadirachta indica Leaf Meal                                                                                                          21

2.10  Inclusion Levels of Azadirachta. indica Leaf Meal                                                                                                          23

2.11  Phytochemical Compounds in Azadirachta indica leaves                                                                                                        24

2.12  Therapeutic roles of Azadirachta indica                                                                                                        25

2.12.1  The Antibacterial Potential of Azadirachta indica                                                                                                        26

2.12.2  Anti-inflammatory Agent in Azadirachta indica                                                                                                        27

2.13  Anti-nutritional factors in Azadirachta indica leaves                                                                                                        28

2.14  Synergistic combination of Herbal Leaf Meals (Moringa oleifera leaf meal and

         Azadirachta indica leaf meal)                                                                                                         28

2.15  Blood                                                                                                        29

2.16  Blood Chemistry                                                                                                 32

2.17  Haematological indices                                                                                                       33

2.18  Importance of carcass quality                                                                                                       34


CHAPTER 3:  MATERIALS AND METHODS

3.1  Experimental Site                                                                                                                36

3.2  Experimental Materials Used                                                                                                          36

3.3  Experimental Birds and Management                                                                                             36

3.4  Experimental Diets                                                                                                          37

3.5  Chemical Analysis                                                                                                    41

3.5.1  Moisture content determination                                                                                           41

3.5.2  Crude Protein determination                                                                                           41

3.5.3  Total Ash determination                                                                                           42

3.5.4  Fat determination                                                                                           43

3.5.5  Crude Fibre determination                                                                                           43

3.5.6  Nitrogen Free Extract determination                                                                                           44

3.6  Experimental Design                                                                                                       44

3.7  Data Collection                                                                                                 45

3.7.1  Feed intake (g)                                                                                                             45

3.7.2  Average Body weight gain (g)                                                                                                             45

3.7.3  Feed conversion ratio                                                                                                           46

3.7.4  Data on Average weekly mortality Rate (%)                                                                                                                 46

3.7.5  Carcass quality examination                                                                                              46

3.8  Haematology and Blood Serum Analyses                                                                                                                   47

3.9  Cost Benefit Analyses                                                                                                   48

3.10  Statistical Analyses                                                                                                   49


CHAPTER 4:  RESULTS AND DISCUSSION

4.1  Proximate Composition of Dried Moringa Oleifera Leaf and Dried Azadirachta

        indica Leaf                                                                                                           50

4.2  Weight Gain, Feed Intake and Feed Conversion Ratio Parameters                                                                                                51

4.2.1  Daily feed intake                                                                                                        52

4.2.2  Daily weight gain                                                                                                                   53

4.2.3  Feed conversion ratio                                                                                                           53

4.2.4  Mortality rate                                                                                                            54

4.3  Cost Benefit Analyses of Broiler Chickens at Starter Phase                                                                                                         54

4.3.1  Cost per kilogram of feed                            55

4.3.2  Cost of production          55

4.3.3  Cost per weight gain                    56

4.3.4  Revenue                                                                                                    56

4.3.5  Gross Revenue             56

4.4  Performance Parameters of Broilers Chickens fed Graded Levels of Moringa

        oleifera and Azadirachta indica leaf meals at Finisher phase                                                                                                         56

4.4.1  Daily feed intake                                                                                                        57

4.4.2  Daily weight gain                                                                                                                   58

4.4.3  Feed conversion ratio                                                                                                           58

4.4.4  Mortality rate                                                                                                            59

4.5  Carcass Characteristics                                                                                          60

4.6  Organ Response Analysis of Broiler Chickens fed Graded Levels of Moringa

       oleifera and Azadirachta indica leaf meals at Finisher phase                                      61

4.7  Haematological Parameter of Broiler Chickens fed Graded Levels of Moringa

        oleifera and Azadirachta indica leaf meals at Finisher Phase                                                                                                         62

4.7.1  Red blood cells                                                                                                           63

4.7.2  White blood cell                                                                                                            64

4.7.3   Haemoglobin                                                                                            64

4.7.4   Packed cell volume                                                                                                      65

4.7.5  Mean courpuscular volume (MCV)                                                                                                                     65

4.7.6  Mean copuscular haemoglobin                                                                                             66

4.7.7  Mean copuscular haemoglobin concentration (MCHC)                                                                                                    66

 

4.8  Serum Biochemical Indices of Broiler Chickens fed the experimental diets at

        Finisher Phase                                                                                                         67

4.8.1  Total Protein                                                                                                      67

4.8.2  Albumen                                                                                                   68

4.8.3  Cholesterol                                                                                               68

4.8.4  Creatinine                                                                                                 69

4.8.5  Aspartate aminotransferase (AST)                                                                                                        69

4.8.6  Alanine aminotransferase (ALT)                                                                                                        69

4.9  Cost Benefit Analyses of Broiler Chickens at Finisher Phase                                                                                                         70

4.9.1  Cost per kilogram of feed                            70

4.9.2  Cost of feed consumed                                                                                                  71

4.9.3  Cost of production          71

4.9.4  Cost per weight gain:                   71


CHAPTER 5:  CONCLUSION AND RECOMMENDATIONS

5.1   Conclusion                                                                                                73

5.2   Recommendations                                                                                    73

References                                                                                                74


 


 

LIST OF TABLES

2.1:  Normal Haematological Indices of Blood                                                                                                        33

2.2:  Normal Haematological range in Broiler Chickens                                                                                                   34

3.1:   Percentage composition of Experimental Diets at Starter Phase (1-5week)                                                                                                      39

3.2:   Percentage composition of Experimental Diets at Finisher Phase (5-8week)                                                                                                      40

4.1:   Proximate composition of Dried Moringa oleifera leaf                                                                                                            50

4.2:   Performance Parameters of Broilers fed Graded Levels of Moringa oleifera and

         Azadirachta indica leaf meals at Starter Phase                                                                                                 52

4.3:  Cost Benefit Analyses of Broiler Chickens fed Graded Levels of Moringa oleifera

          and Azadirachta indica leaf meals at Starter Phase                                                                                                   55

4.4:  Performance Parameters of Broilers Chickens fed Graded Levels of Moringa

        oleifera and Azadirachta indica leaf meals at Finisher Phase                                                                                                 57

4.5  Carcass Analyses of Broiler Chickens fed Graded Levels of Moringa oleifera and

        Azadirachta indica leaf meals at Finisher Phase                                                                                                 60

4.6:  Organ Response Analysis of Broiler Chickens fed Graded Levels of Moringa oleifera

        and  Azadirachta indica leaf meals at Finisher Phase                                                                                                 61

4.7:  Haematological Indices of Broiler Chickens fed Graded Levels of Moringa oleifera

        and Azadirachta indica leaf meals                                                                                                 63

4.8:  Serum Biochemical Indices of Broiler Chickens fed Graded Levels of Moringa

         oleifera  and Azadirachta indica leaf meals                                                                                                 67

4.9:  Cost Benefit Analyses of Broiler Chickens fed Graded Levels of Moringa oleifera

        and Azadirachta indica leaf meals at Finisher  Phase                                                    71

 


  

 

 

CHAPTER 1

INTRODUCTION

1.1   BACKGROUND OF THE STUDY

In livestock keeping, Poultry especially broiler and layers are the major enterprise practicing in almost every part of Nigeria. They have been effective sources of livelihood to many Nigerians, as they have short generation interval (Akinmutimi and Onwukwe, 2002). Their vast benefits include source of income, quality protein and quick returns on investment (Ukachukwu, 2008). The target of a good modern farmer is to produce healthy birds with quality meat and eggs without harmful residues and within a short time interval. For this to be successful, availability and supply of feedstuffs to meet the nutrient requirements of the poultry birds for their optimum production should be considered as the major factor (Ukachukwu, 2008) in addition to proper hygiene, potable water and management (Saxena, 2008). To maximize the production of these products to meet the animal protein requirements for human and other industrial needs, high cost of feed is one of the major problems poultry enterprise has as the prices of conventional feed stuffs are still high (Akinmutimi et al., 2000).

The major cause of this challenge is traced to be stiff competition for energy and protein feed stuffs between humans and livestocks due to conventional feedstuffs used in poultry feeds are also use in human diets (Ogbuewu et al., 2010c).

Also, high exchange rate results in high cost of conventional vegetable protein such as soybean and groundnut cake in developing countries like Nigeria due to most of these feed materials are still being imported (Esonu et al., 2006). Because of the increasing cost of these ingredients, many research work have been conducted to overcome these challenges, and this has triggered the search for alternative means to produce birds at reduced cost using leaf meals as substitute to conventional resources in the formulation of poultry diets.

Broiler birds have the ability to convert raw feed stuffs and by-products into high proteinous food which is important in improving human nutritional standards (Mukhtar, 2007). However, several studies have revealed that leaf meals of plants such as Alchornia cordifolia, Leuceana leucocephala, Moringa oleifera Amarathus cruentus, Mucuna utilis, Azadirachta indica,Curcuma longa and Cinnamomum zylenicum are important feed resources and organic supplement to many monogastrics including poultry. Organic supplements have been proved to be beneficial in amendment of deficiencies in feed without causing any harm to human and animal health as well as the environment. They also play a vital role in promoting livestock performance, reducing cost, stimulate digestive organs, increase profitability and nutritional value of feed (Alagbe and Soares, 2018). Some of these leaf meals contain phytochemical compounds.

Phytochemicals are compounds produced by plants which help them to maintain their healthy life but are not essential nutrients, because some of the phytochemicals decrease nutrient intake when they are in excess (Ansari, 2012). These chemicals occur naturally in plant parts including the leaves. The biological functions they perform include antioxidant activities, physiological agents, antimicrobial agents and so many other functions and this depends on the type of phytochemical available. With this reason, researches have been directed to the use of plants with phytogenic effects as feed stuffs for poultry (Ansari, 2012). Many plants are beneficial in some aspects they are derived from their specific bioactive compounds (Kamel, 2000). Herbs are Phytogenic additives often called phytobiotics (Ansari, 2012) and are recommended to enhance metabolic processes and the health condition of livestock (Panagasa et al., 2012).

Moringa oleifera is a deciduous soft wood tree which grows fast with drought-resistant ability, native to the southern foothills of the Himalayas in northwestern India but grows in several African countries, like Nigeria (Anwar et al., 2007). The leaves are medicinal as they have antibacterial and antifungal activities (Nickon et al., 2008), natural antioxidant compounds (Sreelatha and Padma, 2009), such as chlorogenic acid and caffeic acid (Siddhuraju and Becker, 2003). The press cake has protein that is positively charged and because of this potential, it is used as an antibiotic (Ologhobo et al., 2014).

Azadirachta indica commonly known as neem is a non-leguminous tree that belongs to the family Meliceae (Arbonnier, 2002). This tree species is believed to be originated from Indian subcontinent (Girish and Shankara, 2008) and Senegal (Orwa et al., 2009). It is a fast-growing tree which has a height of about 20 metres. Many bioactive compounds present in Azadirachta indicainclude azadirone, vilasinin, C-secomeliacins, promeliacin, limonoids, gedunin, azadirachtin, nimbin, salanin and other non-iosprenoids, as well as protein/amino acids, polysaccharides, sulphurous compounds, polyphenolics such as flavonoids, their glycosides, dihydrochalcone, coumarins, tannins and aliphatic compounds (Biswas et al., 2002). However, more than one hundred and thirty-five compounds have been identified from different Azadirachta indica tree (Unigwe et al., 2016).

Medicinal plants contain several bioactive chemical compounds which are mainly stored in the secretory glandular epidermal trichomes present in the leaves (Prakash et al., 2006). Recently, the concerns of scientists are reducing the abdominal fat and increasing the valuable parts of carcass (Al-kassie, 2009). Numerous researchers have observed in their studies that Azadirachta indica leaf meal and Moringa oleifera leaf meal have cholesterol lowering effect in humans and animals due to the presence of bioactive compounds in them. There is evidence that combination of the two leaf meals in the feeds of poultry would yield synergistic results as regards to weight gain, feed efficiency, lowered mortality and increased live ability in poultry birds.


1.2 STATEMENT OF PROBLEM

Brioler Chickens have the ability to convert raw feed stuffs and by-products into high proteinous food. They are not very hardy birds and can get sick often if not properly managed. Leaf meals of medicinal plants such as Moringa oleifera and Azadirachta indica have been identified as plants with several bioactive chemical compounds which help in maintaining life by promoting performance of livestocks and nutritional value of feed.

The problems of leaf meals are known to be high fiber content and the presence of anti-nutritional factors in them which affect the food value by reducing digestion or absorption especially when consumed in excess. They may also chelate with the nutrients and form binding factor with the food values thereby, causing nutrient deficiency. They may also change the blood profiles. These factors limit the inclusion of medicinal leaf meals in larger quantities due to the techniques for detoxifying these anti-nutritional factors have not been developed.

Moringa oleifera has good nutritional value but bulky quantities had to be collected to make a reasonable quantity of leaf meal to meet the subsequent inclusion levels which made the work tedious as much quantities yield small quantity of leaf meal. Consequently, the bitterness of Azadirachta indica leaf meal impacted objectionable taste to the feed which limited the feed intake of the chicks fed the treatment diets contained the leaf meal.


1.3    OBJECTIVES OF THE STUDY

Growth performance and blood profiles are important indices of physiological state of animals (Khan and Zafer, 2005). Serum biochemistry and hematological studies have been found   useful to determine clinical condition of the health status in livestocks and birds because whatever an animal ingests either in solid or liquid form must report in the blood profile (Nodu et al., 2016). Variation in blood picture as a result of certain conditions such as stress, infections and toxicity and blood constituents provide vital information for clinical investigations and nutritional evaluation (Aderemi 2004; Khan and Zafer, 2005).

For the fact that so many plants with medicinal properties do not form residual (Tipu et al., 2006), the objective of this work were to:

1.      determine the chemical composition of the test ingredients;

2.      determine the proximate composition of the experimental diets;

3.      investigate the response of broiler chicks to Moringa oleifera and Azadirachta indica on growth performance, carcass and organ characteristics;

4.      determine the haematology and serum biochemical indices of broiler chickens fed the treatment diets;

5.      evaluate cost benefit analysis of broiler chickens using the treatment diets.

 

1.4    JUSTIFICATION

The consumption of Poultry meat is steadily increasing worldwide as they are excellent sources of high quality nutrients in the human diet.  Human health is related directly to the environment, and in particular the nature and quality of the food and with this reason, production of food from animal products should focus on combination of producing healthy birds with quality meat and eggs without harmful residues, within a short time interval and at reduced cost to enhance effective livelihood of many Nigerians via broiler production. However, the major limitation in the utilization of leaf meals is traced to be their high fibre contents and in some cases, presence of toxic factors or metabolic inhibitors such as saponin, phytate, tannin, oxalate, enzyme inhibitors and alkaloids, as they may chelate the nutrients and form a biding factor with the food values thereby making the nutrients non-bioavailable in the system and also may change the blood profiles. The concentrations of these anti-nutritional factors seem to vary with species and plant part concerned.

Although, Moringa oleifera and Azadirachta indica leaf meals have anti-nutritional factors but the concentrations are found to be low. They also have bioactive compounds such as carotenoids, phenolic compounds, flavonoids, azadirone, promeliacin, limonoids, gedunin, vilasinin, C-secomeliacins, azadirachtin, nimbin, salanin etc. These compounds exhibit phytogenic additive properties that can support the digestive enzymes action, improve feed intake, feed conversion ratio (FCR) and carcass yields in broiler. They also have medicinal potentials like antibacterial, antiviral, antifungal, antiprotozoal, hepatoprotective, lymphocyte cells development and anticoccidial effect in broilers. Therefore the leaf meals will serve as supplements for antibiotics, antiviral, antifungal, antiprotozoal and anticoccidial to poultry farmers especially those who have minimal access to veterinary services, those who could not afford to purchase veterinary drugs and those who did not have knowledge of drug administration. As the leaves can be found within our environment, it will also reduce cost in terms of feed cost and cost of inviting veterinary Doctor to farm. This will also lead to production of quality meat without presence of chemical residues to entire Nigerians as organic acids are digestible and do not form residuals in poultry products.


 

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