MODELLING THE RISK FACTORS OF DIARRHOEA RELATED MORBIDITY AMONG UNDER FIVE CHILDREN IN NIGERIA

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ABSTRACT


Diarrhoea remains the major cause of morbidity and mortality among under-five children in many developing countries including Nigeria. This study examined sex of the child, age of the mother, parity, birth order, when the child was put into breastfeeding, mother’s highest level of education, place of residence, wealth index, toilet facility and source of drinking water in association with diarrhoea among under-five children in Nigeria. Data were obtained from the 2013 Nigeria Demographic and Health Survey. The data were analysed using both logistic regression and the exponentiated logistic regression where one shape parameter was introduced into the binary logistic regression to make a two shape parameter distribution. These models were used to determine the risk factors of diarrhoea using predictors like age of the mother, birth order, mother’s highest educational level, sex of the child, place of residence, wealth quintile, toilet facility, when the child was put into breastfeeding, source of drinking water and parity. The results obtained from binary logistic regression were compared with the result from exponentiated logistic regression using AIC. A total of 2,924 or (10.6%) children under the age of five were captured in the two weeks preceding the survey. Result shows that majority of children who were diagnosed of diarrhoea were children of mothers whose age were less than 20 years (15.0%), children whose birth order were 4+ (11.3%), children of women with parity 4+ (10.7%), and children of mothers with no education (12.8%). The prevalence of diarrhoea was also found to be slightly higher in males (10.5%) than female children (10.4%). The percentage of children with diarrhoea in the rural areas (11.4%) was higher than that of the urban (9.3%).  In terms of source of drinking water, children whose household obtain drinking water from unprotected sources show higher prevalence of diarrhoea (12.1%) as compared with the protected sources of drinking water. Risk factors that were found to be significantly associated with diarrhoea morbidity among children under five years of age were the mother’s age (WS = 163.02, p < 0.0001), birth order (WS = 175.31, p < 0.0001), mother’s educational level (WS = 3.33, p < 0.0343), parity (WS = 122.47, p < 0.0001) and source of drinking water (WS = 14.05, p < 0.0001) while other risk factors like sex of the child, place of residence, wealth index and toilet facilities were not statistically significant (p < 0.05). The findings show that among the risk factors considered, age of the mother at birth was the most significantly related to the incidence of diarrhoea among under-five year children in Nigeria. 





TABLE OF CONTENTS

Title Page                                                                                                                  i

Declaration                                                                                                                ii

Certification                                                                                                              iii

Dedication                                                                                                                 iv

Acknowledgements                                                                                                v

Table of contents                                                                                                      vi

List of tables                                                                                                             viii

List of Abbreviations                                                                                               ix

Abstract                                                                                                                     x

 

CHAPTER 1:  INTRODUCTION

1.1  Background of the Study                                                                                  1

1.2  Statement of the Problem                                                                                 3

1.3  Aim and Objectives of the Study                                                                    4

1.4  Significance of the Study                                                                                  5

1.5  Scope of the Study                                                                                             5

 

CHAPTER 2:  LITERATURE REVIEW

2.1   Diarrhoea Related Morbidity                                                                        6

2.2   Effects of Diarrhoea                                                                                         12

2.3   Diarrhoea Morbidity and Its differentials                                                    14

2.3.1  Age-Gender differential                                                                                14

2.3.2   Education and diarrhoea morbidity                                                          14

2.3.3   Environmental Factors and diarrhoea morbidity                                    15

 

CHAPTER 3: METHODOLOGY

3.1   Source of Data                                                                                                  18


 

 

3.2  Variable Specification                                                                                      19

3.3  Method of Analysis                                                                                          19

3.3.1 Binary logistic regression                                                                              21

3.3.1.1 Parameter estimation in logistic regression                                            22

3.3.1.2 Wald test for logistic regression                                                                24

3.3.1.3 Performance comparison among logistic regressions                           25

3.3.1.4 Likelihood ratio test                                                                                                26

3.3.2 The Exponentiated binary logistic regression (EBLR)                              26

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CHAPTER 4: RESULTS AND DISCUSSION                                      

4.1 Results                                                                                                                 30

4.1.1 Bivariate results                                                                                              30

4.1.2 Multivariate results                                                                                        33

4.2 Discussion                                                                                                           44

 

CHAPTER 5: CONCLUSION AND RECOMMENDATION

 

5.1 Conclusion                                                                                                          48

5.2 Recommendations                                                                                             49

REFERENCES                                                                                                          51                                                                                           

APPENDICES                                                                                                          58





 

LIST OF TABLES

 3.1    Selected variables for the study                                                                              19

 

 4.1    Distribution of children under five years of age by

           their diarrhoea morbidity status in the two weeks before

           the survey by selected characteristics, Nigeria, 2013                                          32

 

 4.2   Summary of results for test of multicollinearity                                                    34

 4.3   Binary logistic regression result showing risk factors of

          diarrhoea morbidity among under-five year children in

          Nigeria (Full model)                                                                                                 36

 

 4.4   Binary logistic regression result showing risk factors

          of diarrhoea morbidity among under-five year children

          in Nigeria (Reduced model)                                                                                    38

                   

4.5   Exponentiated binary logistic result showing risk factors

         of diarrhoea morbidity among under-five year children in

         Nigeria based (Full model)                                                                                       40

 

4.6    Exponentiated binary logistic result showing risk factors

          of diarrhoea morbidity among under-five year children in

 Nigeria (Reduced model)                                                                                         42       

 

4.7    Comparative result of binary logistic regression and

          the proposed exponentiated binary logistic regression

          for both full and reduced models.                                                                          43       

 

 

 

                

 

 

LIST OF ABBREVIATIONS:

AIC                 =          Akaike information Criterion

CDF                =          Cumulative Density Function

LRT                =          Likelihood Ratio Test

MLEs              =          Maximum Likelihood Estimators

NEEDS           =          National Economic Empowerment and Development Strategy

NPC                =          National Population Commission

NDHS             =          Nigeria Demographic and Health Survey

PDF                =          Probability Density Function

R.C                  =          Reference Category

UNICEF         =          United Nation Children Funds

VIF                  =          Variance Inflation Factor

WHO              =          World Health Organization

 

 

 

 


CHAPTER 1

INTRODUCTION

1.1   BACKGROUND TO THE STUDY

Globally, diarrhoea related morbidity and mortality among under-five children have raised a major concern to health practitioners and governments. Several studies have been conducted to unravel the determinants of diarrhoea ailment and death among children under the age of five in different parts of Africa (Sinmegn et al., 2014; Kawakatsu et al., 2017; Mohamed et al., 2016; Elmi and Dioso, 2017; Magbagbeola et al., 2017; Nwaoha et al., 2016).

Diarrhoea is described as the major killer disease of children in the 0 – 5 age bracket (World Health Organization, 2000). In 2013, of the 6.7 million deaths among under-five children worldwide, about half died due to communicable diseases, while diarrhoea killed over half a million children (Thiam et al., 2017). Although death caused by diarrhoea has decreased in the last 25 years, morbidity from diarrhoea among under-five children in West Africa is still on the increase (Takele et al., 2019). The scourge of diarrhoea remains one of the main disease burdens among under-five children in developing countries.

In Nigeria, increase in diarrhoea morbidity as evidenced from the 2013 Nigeria Demographic and Health Survey (NDHS, 2013) has attracted widespread public discussion on child’s health. The loss of too much water brought about by diarrhoea contributes significantly to illness and death among under-five children. Though this situation may without much pains be treated, being subjected to germs responsible for diarrhoea is often attributed to the drinking of infected water besides unhygienic practices. Most of the low-income countries are faced with this endemic disease.

According to the United Nations’ sustainable development goals report 2011, the alarming rates of age zero to five children morbidity continued to be in Sub-Saharan Africa. Estimates show that at least one in eight children die before their fifth birth day (129 deaths per 1000 live births) which is nearly twice the average in developing regions and about 18 times the average in developed regions (UNICEF, 2016).

Studies conducted in developing countries have focussed on socio-economic and environmental variables that can affect the incidence of diarrhoea, particularly housing conditions, parental education, and income. However, it is widely recognized that diarrhoea is common among developing countries which is determined by the age and gender of the child, quality and quantity of water, having access to good toilet facilities, place of residence, mother’s level of education, economic status, feeding practices and the sanitary condition around the environment (Stephen, 2010). Children living in households with poor access to quality water supply, poor toilet facilities, poor sanitary environment and among others, have been identified to have increased risk of viral, bacterial, and parasitic pathogens that predispose them to diarrhoea infection and death. (Kermani et al, 2010).

Also, according to (Black and Fawcett, 2008), more than 1.2 billion children worldwide gained access to cleaner environment between 1990 and 2004, even with this progress, some 41% of the world’s population an assessed 2.6 billion people including 980 million children lack access to proper sanitation. Inadequate cleanliness, bad hygiene and quality drinking water are great world-wide challenge. But, researchers in their respective studies have developed models that have helped to identify possible risk factors of diarrhoea related morbidity among under-five children.

The health of the mother and child is of great importance and is a good reflection of the current health situation of a nation. A good child’s health is synonymous with wealth of the future (Tawiah, 2005). This and more provided the motivation to embark on this study with the objective of identifying the key factors such as sex of the child, age of the mother, parity, birth order, when the child was put to breastfeeding, mother’s highest level of education, place of residence, wealth index, toilet facility and source of drinking water are responsible for high prevalence of diarrhoea among under-five children in Nigeria. The results hopefully would support evidence-based interventions to minimize diarrhoea disease burden among under-five children in Nigeria.

 

1.2     STATEMENT OF THE PROBLEM

Update from World Health Organisation (2017), indicates that diarrhoea ranks as the number two reason of mortality involving under-five children globally, and is the cause of the death of about 525,000 children annually. It has been estimated in Africa, that every child under aged five experience at least five (5) episode of diarrhoea each year and about 800,000 children die of this illness annually.  

In Nigeria, diarrhoea is the second killer of children under age five and responsible for about 16 percent of childhood deaths yearly (Dairo et al., 2017). Moreover, it was estimated by (WHO, 2009) that, in Nigeria a total of 151,700 children under aged five die due to diarrhoea annually. Consequent upon, diarrhoea leaves a huge responsibility on society. In addition, diarrhoea morbidity in the long-term undermines the nutritional status, growth, fitness, cognition and performance of children (Kosek et al., 2003; Institute of one World Health, 2000).

Therefore, there is need to study those things responsible for increase of diarrhoea related morbidity among under-five year children in Nigeria using data from the 2013 Nigeria Demographic and Health survey.

 

1.3  AIM AND OBJECTIVES OF THE STUDY

The aim of this study is to identify of the risk factors of diarrhoea related morbidity among children under five years of age in Nigeria. The specific objectives of this study are;

i)                   To identify the risk factors of diarrhoea related morbidity among under-five children in Nigeria, using binary logistic regression model;

ii)                 To identify the major risk factors of diarrhoea related morbidity among under-five children in Nigeria, using exponentiated binary logistic regression model;

iii)              To compare the results obtained using the exponentiated binary logistic regression with that of binary logistic regression model.

 

1.4      SIGNIFICANCE OF THE STUDY

The study will be beneficial to the government, the general public, and the health practitioners because it will help to identify the key agents which increase diarrhoea sickness among under-five children in Nigeria.

Also, to other researchers it will serve as a springboard and enhance further research work in the areas of protected source of drinking water, mothers level of education, mother’s age, and among others.

 

1.5   SCOPE OF THE STUDY

The scope of this study is limited to the factors such as sex of the child, age of the mother, parity, birth order, when the child was put into breastfeeding, mother’s highest level of education, place of residence, wealth index, toilet facility, and source of drinking water using binary logistic and exponentiated binary logistic regression model to analyze the diarrhoea related morbidity among children within the age group of zero to five years in Nigeria.

 

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