ABSTRACT
This study was carried out on measles infection among patients attending Rasheed Shekoni Teaching Hospital, Dutse Jigawa State. A total number of 100 subjects were screened at Rasheed Shekoni Teaching Hospital from January, 2021 to July, 2023. The results show that individuals who did not received at least one dose of measles vaccine had the highest prevalence, 54.14 percent, while those who received at least one dose of measles vaccine had a prevalence of 45.86%. The prevalence of measles infection was seen among children of age bracket of 0 to 5 years age bracket which covered (44.87%) for male and (55.13%) for female due to the parent/guardian for various reasons. The percentage prevalence of measles infection among children of three to five years is 35 (44.87%), followed by 0 to 5 years with 35 (44.87%) for male and 43(55.13%)for female, this result indicate that the body building of children under five years immunological setting is working in terms of body immunity.
TABLE OF CONTENTS
Title page …………………………………………………………….………………………
i
Declaration………………………………………..……………………………………………....
ii
Certification…………………………………………….…………………………………...…...
iii
Approval page……………………………………………………..………………………..…..
iv
Dedication………………………………………………….……………………………………..v
Acknowledgments…………………………………………………………………………….…vi
Table of
Contents……………………………………………………………………………….vii
Abstract………………………………………………………………………………………….ix
CHAPTER
ONE
1.0 Introduction …………………………………………………………………………………1
1.1 Statement of the Research Problem
…………………………………………..……..………2
1.2 Aim and Objectives …………………………………...…………………………………….2
1.3 Justification of the Study
……………………………………………………...……………2
1.4 Scope and Limitations of the Study ……………………………………………….……3
1.5. Definition of the Terms………………………………………………………………………3
CHAPTER
TWO
2.0 Literature review …………………………………………………….……………….…..…4
2.1 History of measles infection
…………………………………………….................……...…6
2.2 Life cycle of measles infection………………………………………..……………………...7
2.3 Incidence of measles infection………………………………………….……………….
…8
2.4 Epidemiology of measles infection………………………………………….……………
...8
2.5 Diagnosis of measles infection………………………………………….…………………
..8
2.6 Sign and symptoms of measles infection…………………………………….….…………..9
2.7 Prognosis of measles infection…………..……………………………………..…………..
.9
2.8 Treatment of measles infection…………………..…………………….…….……………..
10
2.9 Prevention and control of measles
infection…………….…………………...……………..10
CHAPTER
THREE
3.0 Methodology…………………………………………………….………………………….11
3.1 Study Area ………………………………………………………….……………….11
3.2 Population of the Study
……………………………………………………….…..……….11
3.3 Method of Data Collection…………………………………………..……………………..11
3.4 Data Collection……………………………………………………………………………...12
3.5 Statistical
Analysis…………………………………………………………………………..12
3.6 Ethical Issue………………………………………………………………………………...12
CHAPTER
FOUR
4.0 Result
Presentation/Interpretation and Discussion………………………………...............13
4.1 Result ……………………………………………………………………..............................13
4.2
Discussion…………………………………….…………………….……..….…………….14
CHAPTER
FIVE
5.0 Summary, Conclusion and
Recommendations…………………………….….…………..16
5.1 Summary …………………………………………………………………..……………….16
5.2 Conclusion…………………………………………………………..………………………16
5.3 Recommendations……………………………………………………..……………………17
References……………………………………………………………..…………………….18
CHAPTER ONE
1.0 Introduction
Measles is a highly contagious systematic viral illness
caused by RNA virus of the genus morbillivirus, in the family paramyxoviridea
(Gerald et.al, 2000). Human and primate are the only natural host of the
measles virus, the main symptoms are fever, dry cough, red eyes, light
sensitivity, a runny nose, sore throat, white spot in the mouth a
characteristic that typically start on the first and spread down the body to
the trunk and legs, (Gerald et. al., 2000). Most of the people recover
within a couple of weeks but up to 20% develop complication that may include an
ear infection, bronchitis, pneumonia, area or blindness, people who are
malnourished, have a Vitamin A deficiency or have compromised immune system,
are frequently more severely affected. Women who are pregnant when they are
infected with measles are at greater risk of miscarriage or of premature labour
(Gerald et al, 2000).
Before the measles vaccine will be introduced, almost all
children caught the disease. In the United States and other highly populated
populous rare sporadic cause may occur in susceptible persons of any age,
although disease is likely to occur in those born before 1959, before the time
Moses will be highly endemic and most person acquired measles during childhood
(Cherry et. al, 2002).
Measles is now extremely rare in developing countries,
because of the successes of developing countries where the nation is
responsible for approximately I million deaths worldwide each year; almost all
of the children recover with the measles in developing countries. It is also
leading cause of blindness in those regions. Global eradication of measles with
next to 10-20 years in feasible morbidity and mortality, particularly in
developed countries, despite the introduction of inadequate measles virus
vaccine which have greatly reduced in the 1960 (WHO, 2009). The window period
of infection for infants lies between the disappearing of maternal antibody
protection and vaccine administration (Manchester and Rall, 2001). Infection is
transmitted via airborne exposure from coughing, sneezing or close contact with
nasal secretion, measles virus remain active in air for 2 hours. It enters the
body through respiratory system and spread systematically by infection lymphoid
cells. Infection and spreading is complex process. Structure and protection of
measles virus are important determination virus tropisms and pathogenesis
(Yanagi et. al, 2006). Measles outbreak can result in epidemic that
cause many deaths, especially among young malnourished children. In countries
where missiles has from other countries remain an important sources of
infection (Babanniyi et. al, 1995).
Severe complications from measles can
be avoided through supportive care that ensure good nutrition, adequate fluid
intake and good treatment of dehydration with who recommended oral rehydration
solution. Risk Solutions replaced flute and other essential elements that are
lostthrough the area to treat eye and car infection and pneumonia, (Adetunji 2007).
All children in developing countries
diagnosed with measles should collect two doses of Vitamin A supplements, given
24 hours apart, treatment restore low vitamin A Level or even in well-nourished
children and can help to prevent eye damage and blindness. Vitamin A supplement
have shown to reduce the number of deaths from measles infection by 15%,
(Adetunji 2007).
1.1 Statement of the Research Problem
Measles infection is the major problem in our community
today. It is widely spread every day and a lot of children have been infected
with the disease, the community and people are encouraged to have an ideal
knowledge of measles prevention and control since the disease kills each and
every gender (male and female) and causing further infection to children.
1.2 Aim and Objectives
1.2.1 Aim:
The Aim of this research is to establish the occurrence of
measles infection among children attending Rasheed Shekoni Teaching Hospital Dutse (RSTH), Jigawa State.
1.2.2 Objectives:
Ø To determine
whether there is association between the measles infection and their
residences.
Ø To determine the
level of infection among children.
Ø To determine the
decline in the incidence of measles from 2021 - 2023
Ø To determine the
Prevalence of measles infection in immunized and non- immunized children in
RSTH from 2021 to 2023
1.3 Justification of the Study
Measles infection is one of the spread diseases that infect
children. The project is designed to survey the prevalence of measles infection
which needs to be defined and ruled out among children attending Rasheed Shekoni Teaching Hospital Dutse.
This information is necessary in any attempt to access physical. weakness of
measles among children.
1.4 Scope and
Limitations of
the Study
The study focuses on children aged 0-5 years who visit a
specific hospital. The target population includes both inpatients and
outpatients attending the hospital during a specified period. The primary
objective of the study is to determine the prevalence of measles infection
among the target population. Researchers will collect data on confirmed measles
cases within the hospital during a defined time frame. The study will be
conducted in a single general hospital to ensure consistency in data collection
and minimize confounding factors. Also the study will rely on medical records
and laboratory reports of children visiting the hospital. Confidentiality and
ethical considerations will be strictly adhered to when accessing patient
information. And also the study will be limited to a specific period to capture
a snapshot of measles prevalence during that time. Longer-term trends may not
be analyzed in this study.
1.5 Definition of the Terms
Measles: Measles,
also known as rubeola, is a highly contagious viral infection caused by the
measles virus (MeV). It is characterized by fever, cough, runny nose, red eyes,
and a distinctive red rash.
Prevalence: Prevalence
refers to the proportion of individuals in a population who have a particular
condition or characteristic at a specific point in time or over a defined
period.
Teaching Hospital: A teaching
hospital is a medical facility that is affiliated with a medical school or
university and is involved in the training of medical professionals, including
doctors, nurses, and other healthcare staff.
Infection Rate: Infection
rate is the frequency of new cases of a specific infection within a defined
population over a given time period. In this study, the infection rate
represents the occurrence of new measles cases among children attending the
teaching hospital.
Vaccination Coverage: Vaccination coverage
refers to the proportion of the target population that has received the
recommended doses of measles vaccine.
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