ABSRACT
This work was carried out
to investigate the effects of pterocarpus mildbreadii seed on the HDL- level of
albino rats.High density lipoprotein(HDL) is a fraction of cholesterol,which
helps to transport cholesterol from peripheral of cell to the liver.High
density lipoprotein is carried out to investigate cardio vascular
diseases.Fresh oha seed (pterocarpus mildbreadii seed) was collected from
Amokwe in udi local government Area Enugu state. They were
dried at room temperature
for about a month in an open laboratory space, groud into coarse form and
weighed on an electrical weighing balance. 3% tween-80 was prepared by
dissolving 3% tween -80 in 97ml of distilled water. The grounded pterocarpus
mildbreadii was dissolve in the 3% tween-80.A total of sixteen wistar abino
rats used for this analysis. The rats were divided into 4(four) groups. Group
1contain 4 rats and received 0.5 each of 3% tween-80. Group 2 contain 5 rats
and were administered with 1400mg/kg b.w of pteridocarpus mildreadii solution
Group 3 contain 3 rats and were administered with 2600mg/kg. b.w of
pteridocarpus mildbreadii solution. Group 4 contain 4 rats and were
administered with 500mg/kg. b.w. of Edmard MRT complex.
TABLE OF CONTENT
Tittle page
Certification
Dedication
Acknowledgement
Abstract
Table of content
TABLE OF
CONTENT
CHAPTER ONE
1.0 Introduction
CHAPTER TWO
2.0
Literature review
2.1
lipids
2.2
Classification of lipids
2.3 Triglycerides
2.4 Waxes
2.5
Phospholipid
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2.6 Fatty acids
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2.7 Types of fatty acids
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2.8 Unsaturated fatty acids
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2.9 Essential fatty acids
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2.10
Steroids
2.11 Cholesterol
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2.12 Dietary source & effect of Cholesterol
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2.13 Functions of Cholesterol in the body
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2.14 lipoprotein metabolism
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2.15 very low density lipoprotein (VLDL)
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2.16 low density lipoprotein
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2.17 Function of LDL
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2.18 High density lipoprotein (HDL)
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2.19 Clinical significance
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2.20 Fat soluble vitamin
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2.21 Vitamin A
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2.22 Vitamin D
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2.23 Vitamin E
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2.24 Vitamin K
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2 .25 lipid storage in plants
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2.26 lipid Body structure
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2.27 Unusual fatty acids in seed
triacylglycerol
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2.28 PProperties of lipids
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2.29 Physical properties
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2.30 Chemical properties
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2.31 Rancidity…
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2.32 Roles of lipids
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2.32 Structure
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2.34 Insulation
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2.35 Nerve function
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2.36 Energy source
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2.37 Uses of oha seed (pterocarpus mildbreadii)
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CHAPTER THREE
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3.0 Material
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3.1 Plant seed
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3.2 Animals
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3.3 Equipments
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CHAPTER FOUR
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4.1 Cholesterol activity
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CHAPTER FIVE
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5.0 Discussion and conclusion
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5.1 Discusion
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5.2 Conclusion
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Appendix
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Reference
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CHAPTER ONE
INTRODUCTION
1.0 Pterocarpus
mildbreadii are trees with edible parts successfully budded, pterocarpus
species (P.Soyauxii and P. mildbeadii are reported to have different patterns
of leaf flush, one spontanous and the other intermitted making the first
suitable for commercial production and the second the home production (Okafor
1978). Pterocarpus mildbreadii being the major case study both the vegetable
and the seeds.
The vegetable is majorly used
in our various home for cooking. Pterocarpus mildbreadii (Oha seed) are not
consumed by the people from the eastern part of Nigeria. So it cannot be
majorly stated the content of this oha seed.
The demand for vegetable oils
as a result of diminishing source of oils and fats creates the needs for new
sources as well as exploiting sources that are currently unexploited in order
to supplement the existing ones (Minzangi et al. 2011).
As industrialists continues to
rely mostly on the popular vegetable oil like coconut oil, soyabeans oil,
ground nut oil, palm oil etc. for the preparation and production of their
various products.
Plant lipids also posses
nutritive value and have an impact on human nutrition and the world
economy.more than three quarters of the edible and industrial oils marketed
annually are derived from seed and fruit triglycerol (Schimid & Ohlrogge,
2002). Seeds have nutritive and calorific value which makes them necessary in
diets. They are good sources of edible oils and fats. The amount of energy
provide by 1g of fat and oil when fully digested is more than twice as many
joules of protein and carbohydrate do. Fats makes meals more satisfying, enrich
its flavor and delay the unset of hunger (Odoemelan, 2005). Unfortunately,
insufficient availability of animal protein and the costliness of available
plant protein sources have also increased the need for research on revealing
lesser known under-utilized legumes and oil seeds of nutritive value (Schimid
& Ohlrogge, 2002).
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